https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33133 Tue 28 Aug 2018 13:03:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33129 Tue 28 Aug 2018 12:56:53 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42438 Tue 23 Aug 2022 10:26:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43320 Tue 21 Mar 2023 18:41:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39028 n = 11) with a history of multiple self-reported concussions compared with age- and education-matched controls (n = 13) who have had no history of brain trauma. Diffusion-weighted images were acquired with a Siemens 3T scanner. All participants completed a clinical interview. There were no significant differences between groups on measures of depression, anxiety, stress, or post-concussion symptoms; however, NRL players scored significantly higher on the alcohol use disorder identification test (AUDIT). Voxelwise analyses of DTI measures were performed using tract-based spatial statistics (TBSS) with age and AUDIT scores included as covariates. TBSS revealed significantly reduced fractional anisotropy (FA), and increased radial diffusivity (RD), axial diffusivity (AD), and trace (TR) in white matter regions of recently retired NRL players compared with controls. FA was significantly reduced in the right superior longitudinal fasciculus and right corticospinal tract while TR, RD, and AD were increased in these regions, as well as the corpus callosum, forceps major, right uncinate fasciculus, and left corticospinal tract. In summary, DTI in a small cohort of recently retired professional NRL players with a history of multiple concussions showed differences in white matter microstructure compared with age- and education-matched controls with no history of brain trauma.]]> Thu 21 Apr 2022 15:32:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20840 Sat 24 Mar 2018 08:05:57 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19673 Sat 24 Mar 2018 08:01:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20373 Sat 24 Mar 2018 07:58:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21170 ®, MEDLINE^®, EMBASE, SPORTDiscus™, Scopus, Web of Science, and Informit; using the key search terms: diffusion tensor imaging, diffusion magnetic resonance imaging, diffusion weighted MRI, diffusion MRI, fractional anisotropy, tractography, apparent diffusion coefficient, magnetic resonance imaging, mild traumatic brain injury, mTBI, traumatic brain injury, concussion, sport, athletic and athlete. Observational, cohort, correlation, cross-sectional and longitudinal studies were all included in the current review. Results of the review found eight articles that met inclusion criteria, which included data on 214 athletes and 96 controls. Seven of eight studies reported some type of DTI abnormality, although the neuroanatomical sites involved varied. Although considerable methodological variations exist across studies, the current review suggests that DTI may possess adequate diagnostic sensitivity to detect SRC in affected athletes. Further longitudinal studies are required to demonstrate its discriminate validity and prognostic capacity within this field.]]> Sat 24 Mar 2018 07:58:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28612 p=0.01); the higher body mass index was partially explained by PTHP (R² change=0.07, p=0.001). Otherwise no significant correlation was found among PTHP, functioning, or patient-reported quality of life. This study—which is unique in the homogeneity of the patients, the long follow-up time, and the use of injury severity as an outcome predictor—did not confirm results from previous studies linking PTHP to a worse outcome. Therefore, screening for PTHP might be restricted to specific subgroups such as overweight patients, indicating growth hormone deficiency.]]> Sat 24 Mar 2018 07:38:58 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28122 Sat 24 Mar 2018 07:24:59 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39976 controls group contrast. Post hoc seed-to-voxel analyses using the MVPA cluster results as seeds were performed to characterize functional connectivity abnormalities from brain regions identified by MVPA. MVPA revealed one cluster of abnormal functional connectivity located in cerebellar lobule V. This region of lobule V corresponded to the ventral attention network. Post hoc seed-to-voxel analysis using the cerebellar MVPA cluster as a seed revealed multiple areas of cerebral cortical hyper-connectivity and hypo-connectivity in retired athletes when compared with controls. This initial report suggests that cerebellar dysfunction might be present and clinically important in some retired athletes.]]> Fri 01 Jul 2022 09:51:32 AEST ]]>